Study suggests ACE2, which helps coronavirus invade cells, may be a double-edged sword — ScienceDaily

An enzyme that helps COVID-19 (coronavirus) infect the body also plays a role in inflammation and patient outcomes in inflammatory bowel disease (IBD), according to a new study led by Cedars-Sinai. The findings raise the possibility that anti-inflammatory drug therapies for IBD may aid recovery from coronavirus.

The multisite study, led by Cedars-Sinai and published today in the journal Gastroenterology, focused on angiotensin-converting enzyme 2 (ACE2), which normally plays a crucial health role by activating a hormone that helps regulate blood pressure. But in COVID-19 infections, the SARS-CoV-2 virus binds to ACE2 and uses it to invade and infect cells, “hijacking” them to spread the virus.

To learn more about how ACE2 affects the body, investigators examined its role in Crohn’s disease and ulcerative colitis — two types of IBD that can cause inflammation and scarring (fibrosis) in the digestive tract along with diarrhea, cramping and loss of appetite.

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Turtle Beach CEO ‘Can’t Wait’ for Upcoming PlayStation 5, Xbox Series X on Cheddar

Video game accessories and peripherals maker Turtle Beach surprised the markets with a major beat in earnings as sales of their headsets and devices grew amid coronavirus quarantines. Now, the company is looking forward to the highly anticipated next generation of video game consoles slated for the holidays.

“We’re very excited about the new Xbox and PlayStation launches. They’re coming soon, can’t wait,” Turtle Beach CEO Juergen Stark told Cheddar. “We believe that they will do very, very well post-launch, and that is definitely a long-term driver of, and a catalyst for, all console accessories.”Stark added that gamers tend to “re-accessorize” upon upgrading to new video game systems and that Turtle Beach was already prepared with four new wireless headset models, two for each of the next-gen platforms. And, with the growth of multiplayer gaming, the company sees its headsets continuing to grow right along with the phenomenon.

“People play

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Netflix tests a linear video channel

Netflix takes an old-fashioned approach for its latest feature, Amazon plans a new data center in India and we review the PlayStation 5. This is your Daily Crunch for November 6, 2020.

The big story: Netflix tests a linear video channel

Today in surprising product strategies: Netflix is testing a linear channel in France called Netflix Direct, according to Variety.

To be clear, it’s not a regular TV channel but rather something you access on Netflix’s website. But like a broadcast or cable channel, it ditches streaming’s on-demand side. Instead, you watch whatever movie or TV show is playing right now.

Netflix previously tested a Shuffle button, so apparently it’s very interested in exploring a viewer experience where you just turn the TV on and veg out. The service says it’s testing this in France because “many viewers like the idea of programming that doesn’t require them to choose what

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ULA delays spy satellite launch to Wednesday from Florida

ORLANDO, Fla., Nov. 6 (UPI) — United Launch Alliance plans to try again to send a Department of Defense spy satellite into orbit from Florida on Wednesday.

Liftoff on an Atlas V rocket is planned for 5:22 p.m. EST from Complex 41 at Cape Canaveral Air Force Station.

The launch company had planned a Sunday evening launch, but said Friday that the approach of a storm prompted a change.

“Due to impending weather from Tropical Depression Eta, we are rolling the Atlas V rocket carrying the NROL-101 mission … back to secure the payload and vehicle,” ULA said in an update on its website.

A problem with the rocket’s propellant fuel system foiled a previous attempt the preceding Wednesday evening, and a problem with environmental controls for the satellite forced a delay the day before, ULA said.

The Defense Department’s National Reconnaissance Office says little about any of its satellites,

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How Facebook plans to alert you when there’s a projected presidential winner

Facebook and its photo service, Instagram , said they plan to show users a message at the top of their feeds, and new labels, when a US presidential winner has been projected.



a close up of a sign: Facebook is preparing for the results of the US presidential election. Angela Lang/CNET


© Provided by CNET
Facebook is preparing for the results of the US presidential election. Angela Lang/CNET

The notifications and labels will include a link to Facebook’s voting information center and cite who projected the winner. Facebook and Instagram will add labels that state the projected winner below posts from candidates President Donald Trump and Democratic challenger Joe Biden. The notification that’ll appear at the top of a user’s News Feed will also include a timestamp.

Facebook said in an e-mail that it’s relying on a majority opinion from Reuters and major media outlets, including ABC News, CBS News, Fox News, NBC News, CNN and the Associated Press, to determine when a presidential winner is projected. 



graphical user interface, application: Facebook and Instagram will show you this notification when a presidential winner has been projected. Facebook


© Provided

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Analysis: High-flying U.S. tech stocks get post-election lift, near new highs

NEW YORK (Reuters) – A weaker-than-expected election performance by Democrats and fears of new coronavirus restrictions have prompted investors to double down on high-flying technology stocks, which have come roaring back in recent days to put the Nasdaq within striking distance of a record.

FILE PHOTO: A view of the exterior of the Nasdaq market site in the Manhattan borough of New York City, U.S., October 24, 2016. REUTERS/Shannon Stapleton/File Photo/File Photo

Since Election Day, the tech-heavy Nasdaq Composite is up 6.6%, easily outpacing the 4.2% gain in the broad S&P 500 over the same time. This was partly driven by investors and traders unwinding trades placed on pre-election assumptions of a Democratic sweep which they thought would usher in higher taxes and more regulation.

Polls had forecast Democrats would solidly win the presidency on Tuesday, extend their control in the House of Representatives and potentially win control of the

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Global Transportable Kidney Perfusion System Market to 2025 – by Manufacturers, Regions, Technology, and Product Type

DUBLIN, Nov. 6, 2020 /PRNewswire/ — The “Transportable Kidney Perfusion System Market Insights 2020, Analysis and Forecast Global and Chinese Market to 2025, by Manufacturers, Regions, Technology, Product Type” report has been added to ResearchAndMarkets.com’s offering.

This report is a professional and in-depth study on the current state of the global Transportable Kidney Perfusion System market with a focus on the Chinese market. The report provides key statistics on market of Transportable Kidney Perfusion System. It is a valuable source of guidance and direction for companies and individuals interested in Transportable Kidney Perfusion System industry.

Key points of Transportable Kidney Perfusion System Market Report:
1. The report provides a basic overview of Transportable Kidney Perfusion System industry including: definition, applications and manufacturing technology.
2. The report explores Global and Chinese major players in Transportable Kidney Perfusion System market. In this part, the report presents the company profile, product specifications,

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Down Syndrome-associated gene suppresses age-related corneal clouding — ScienceDaily

An analysis of aging in Down syndrome and hypercholesterolemia mouse models has suggested that a Down syndrome-associated gene, DSCR-1, protects against abnormal vascularization of the cornea and associated corneal opacity (blindness) by suppressing oxidized LDL cholesterol production and new downstream angiogenic signaling in patients with chronic high cholesterol. Epidemiological data suggests that, while the neurological pathology of Down syndrome patients worsens with age, they are also less susceptible to age-related vascular diseases. The responsible genes and mechanisms have not yet been clarified, but DSCR-1 appears to be a strong candidate for a wide range of vascular diseases, such as atherosclerosis and hypertension.

Down syndrome, the most common congenital disease in human genetics, has seen dramatic increases in longevity with advances in modern medicine. Unfortunately, new problems associated with this increased longevity have emerged, such early Alzheimer’s, reduced vision, and muscle weakness. However, unlike the nervous system, the vascular system in

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Fortnite to Return to Apple Devices Via Nvidia Cloud Gaming Service: BBC | Technology News

(Reuters) – Users of Apple Inc’s iPhone and iPad could soon be able to play Epic Games’s “Fortnite” game again via Nvidia’s cloud gaming service, the BBC reported on Thursday.

Nvidia Corp has developed a version of its GeForce cloud gaming service that runs in the mobile web browser Safari, the report said. (https://bbc.in/32jXJqy)

Apple did not immediately respond to a Reuters request for comment, while Epic declined to comment.

Nvidia said it would not comment on any new clients coming to the service, or on the availability of any game on unannounced or unreleased platforms.

The company is expected to announce updates to its GeForce Now service later this month with support to Apple’s iOS.

Apple’s rules require cloud gaming companies to submit each game title in the catalog as a separate app for Apple to review, and the master catalog app would then provide links to the individual

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B2B marketplaces, edtech M&A, breaking into the $1M ARR club

I’ve worked at TechCrunch for a little over a year, but this was one of the hardest weeks on the job so far.

Like many people, I’ve been distracted in recent days. As I write this, I have one eye on my keyboard and another on a TV that sporadically broadcasts election results from battleground states. Despite the background noise, I’m completely impressed with the TechCrunch staff; it takes a great deal of focus and energy to set aside the world’s top news story and concentrate on the work at hand.

Monday feels like a distant memory, so here’s an overview of top Extra Crunch stories from the last five days. These articles are only available to members, but you can use discount code ECFriday to save 20% off a one or two-year subscription. Details here.

B2B marketplaces will be the next billion-dollar e-commerce startups

Marketplaces created for B2B activity

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