The tree of life describes the evolution of life and seeks to define the relationships between species. Likewise, the tree of cell types aims to organize cells in the brain into groups and describe their relationships to each other.
Scientists have long pondered just what the brain’s tree of cell types looks like. Now, an international collaboration led by Dr. Andreas Tolias from Baylor College of Medicine, Dr. Philipp Berens from the University of Tübingen in Germany and Dr. Rickard Sandberg from the Karolinska Institute in Stockholm, Sweden, has published an article in Nature that provides one of the most detailed and complete characterizations of the diversity of neural types in the brain so far.
Uncovering the shape of the tree of cortical cell types with Patch-seq
Neuroscientists mostly use three fundamental features to describe neurons: their anatomy, or how they look under a microscope; their physiology, or how they