More evidence that cellular ‘death by iron’ could be promising avenue of cancer treatment — ScienceDaily

If there is a silver lining in cancer’s chaotic biology, it’s that the same traits that give cancer cells a growth advantage often present opportunities for sabotaging them.

That’s the central idea behind a new research paper published November 23 in Proceedings of the National Academy of Sciences (PNAS) by Xuejun Jiang, a cell biologist in the Sloan Kettering Institute, and Craig Thompson, President and CEO of Memorial Sloan Kettering. They found that cancer cells often exhibit metabolic changes that make them vulnerable to a particular type of cell death called ferroptosis.

Ferroptosis — literally, death by iron — is often triggered by oxidative stress, the buildup in cells of free radicals and other corrosive chemicals that are byproducts of using oxygen to burn fuel for energy. But many cancer cells, which need abundant amounts of energy to grow and divide, have found a way around this problem.

“Genetic mutations

Read More

Lithium Iron Phosphate (LiFePO4) Battery Market outlook, Future Scope, Demands and Projected Industry Growths to 2026

The MarketWatch News Department was not involved in the creation of this content.

Nov 25, 2020 (Market Insight Reports) —
Selbyville, Delaware. The Lithium Iron Phosphate (LiFePO4) Battery Market report upholds the future market predictions related to Lithium Iron Phosphate (LiFePO4) Battery market size, revenue, production, Consumption, gross margin and other substantial factors. It also examines the role of the prominent Lithium Iron Phosphate (LiFePO4) Battery market players involved in the industry including their corporate overview. While emphasizing the key driving factors for Lithium Iron Phosphate (LiFePO4) Battery market, the report also offers a full study of the future trends and developments of the market.

The global Lithium Iron Phosphate (LiFePO4) Battery market is anticipated to reach USD 34.5 billion by 2026, according to a new research published by The marker research report. In 2017, the automotive segment dominated the global market, in terms of revenue. Asia-Pacific is expected to

Read More

Bungie’s DeeJ Moves To Iron Galaxy To Work On New Melee Combat Game

Veteran Bungie staffer David “DeeJ” Dague left the Destiny studio earlier this year, and now he’s landed at Iron Galaxy Studios.

The studio announced that Dague–the former communications director at Bungie–will be the head of communications for Iron Galaxy as it begins work on a new IP. Additionally, Iron Galaxy has appointed Chelsea Blakso as co-CEO alongside Adam Boyes, the former PlayStation boss.

Very little is known about Iron Galaxy’s new game, however, apart from the fact that it will be a “new multiplayer melee combat IP for consoles and PC.”

“Video games bring people together in the spirit of friendly competition,” Dague said in a statement. “This opportunity with Iron Galaxy is a chance to welcome players into a community that we will build with them. There is nothing more exciting than witnessing players discover a brand-new game and come together to define its culture. I’m thrilled to be

Read More

This farmer’s field was once a powerful stronghold in Iron Age Norway

In June, archaeologists began unearthing a Viking ship from a farmer’s field in eastern Norway. The 1,000- to 1,200-year-old ship was probably the grave of a local king or jarl, and it once lay beneath a monumental burial mound. A 2018 ground-penetrating radar survey of a site called Gjellestad, on the fertile coastal plain of Vikiletta, revealed the buried ship.

The Norwegian Institute for Cultural Heritage Research, or NIKU, announced the ship find in 2018, and it announced earlier in 2020 that excavations would begin over the summer to save the vessel from wood-eating fungus. NIKU archaeologist Lars Gustavsen and his colleagues’ recent study is the first academic publication of the survey results, and it includes the previously announced Gjellestad ship burial as well as the other ancient tombs and buildings. In the recently published paper, the radar images reveal the ghosts of an ancient landscape surrounding the royal tomb:

Read More

Hungry plants rely on their associated bacteria to mobilize unavailable iron — ScienceDaily

In nature, healthy plants are awash with bacteria and other microbes, mostly deriving from the soil they grow in. This community of microbes, termed the plant microbiota, is essential for optimal plant growth and protects plants from the harmful effects of pathogenic microorganisms and insects. The plant root microbiota is also thought to improve plant performance when nutrient levels are low, but concrete examples of such beneficial interactions remain scarce. Iron is one of the most important micronutrients for plant growth and productivity. Although abundant in most soils, iron’s poor availability often limits plant growth, as it is found in forms that cannot be taken up by plants. Thus, adequate crop yields often necessitate the use of chemical fertilizers, which can be ecologically harmful in excessive application. Now, MPIPZ researchers led by Paul Schulze-Lefert have uncovered a novel strategy employed by plants to overcome this problem: they release substances from

Read More