Sugar-coated viral proteins hijack and hitch a ride out of cells — ScienceDaily

Researchers from the Universities of Melbourne, York, Warwick and Oxford have shed light on how encapsulated viruses like hepatitis B, dengue and SARS-CoV-2 hijack the protein manufacturing and distribution pathways in the cell — they have also identified a potential broad spectrum anti-viral drug target to stop them in their tracks.

The findings have been published in PNAS today and are important to efforts to develop broad-spectrum antiviral agents.

Professor Spencer Williams from the School of Chemistry at Bio21 said the research will help define a new ‘host-directed’ approach for treating infections by encapsulated viruses.

“One approach to treating viral infections is to make a new drug for each virus that comes along. But it is slow. An alternative and attractive approach is to make a drug against a human target that viruses need to replicate. The same drug can then be used and reused against many different viruses, even

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